105814650 an important question that is in dispute and must be settled; "the issue could be settled by requiring public education for everyone"; "politicians never discuss the real issues".
111410625 a phenomenon that follows and is caused by some previous phenomenon; "the magnetic effect was greater when the rod was lengthwise"; "his decision had depressing consequences for business"; "he acted very wise after the event".
105814291 some situation or event that is thought about; "he kept drifting off the topic"; "he had been thinking about the subject for several years"; "it is a matter for the police".
101060234 the act of providing an item for general use or for official purposes (usually in quantity); "a new issue of stamps"; "the last issue of penicillin was over a month ago".