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Sigma KEE - Interleukin

appearance as argument number 1

(documentation Interleukin EnglishLanguage "Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes). ILs can be divided into four major groups based on distinguishing structural features. However, their amino acid sequence similarity is rather weak (typically 15–25% identity). The human genome encodes more than 50 interleukins and related proteins. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4 T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. [from Wikipedia]") Medicine.kif 3732-3745
(subclass Interleukin Protein) Medicine.kif 3731-3731

appearance as argument number 2

(secretesSubstance WhiteBlookCell Interleukin) Medicine.kif 3748-3748
(termFormat EnglishLanguage Interleukin "Interleukin") Medicine.kif 3747-3747


    (instance ?I Interleukin)
    (hasPurpose ?I
        (exists (?D ?BV ?H)
                (instance ?H Human)
                    (instance ?BV Bacteria)
                    (instance ?BV Virus))
                (instance ?D Destruction)
                (located ?D ?H)
                (instrument ?D ?I)
                (patient ?D ?BV)))))
Medicine.kif 3750-3762

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