ProtonPumpInhibitor - Sigma Knowledge base Browser

appearance as argument number 1

(subclass ProtonPumpInhibitor Medicine)	Mid-level-ontology.kif 11328-11328	PPI is a subclass of medicine
(documentation ProtonPumpInhibitor EnglishLanguage "Proton-pump inhibitors (PPIs) are a class of Medicine that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H+/ K+ ATPase proton pump. They are the most potent inhibitors of acid secretion available. Proton-pump inhibitors have largely superseded the H2-receptor antagonists, a group of medications with similar effects but a different mode of action. PPIs are among the most widely sold medications in the world. The class of proton-pump inhibitor medications is on the WorldHealthOrganization's List of Essential Medicines. Omeprazole is the specific listed example.[from Wikipedia]")	Mid-level-ontology.kif 11330-11341	PPI is a subclass of medicine
(roomTempState ProtonPumpInhibitor Liquid)	Mid-level-ontology.kif 34078-34078	room temperature state PPI and liquid

appearance as argument number 2

(termFormat EnglishLanguage ProtonPumpInhibitor "proton pump inhibitor")	Mid-level-ontology.kif 11342-11342
(termFormat EnglishLanguage ProtonPumpInhibitor "PPI")	Mid-level-ontology.kif 11343-11343

antecedent

(=>
    (and
        (instance ?A ProtonPumpInhibitor)
        (instance ?I Ingesting)
        (agent ?I ?H)
        (moves ?I ?A)
        (instance ?S Stomach)
        (part ?S ?H)
        (holdsDuring
            (ImmediatePastFn
                (WhenFn ?I))
            (and
                (contains ?S ?F1)
                (instance ?F1 Fluid)))
        (holdsDuring
            (ImmediateFutureFn
                (WhenFn ?I))
            (and
                (contains ?S ?F2)
                (instance ?F2 Fluid)))
        (phMeasure ?F1 ?N1)
        (phMeasure ?F2 ?N2))
    (greaterThan ?N2 ?N1))

If All of the following hold: (1) X is an instance of PPI (2) Y is an instance of ingesting (3) Z is an agent of Y (4) X moves during Y (5) W is an instance of stomach (6) W is a part of Z (7) W contains V and V is an instance of fluid holds during immediately before the time of existence of Y (8) W contains U and U is an instance of fluid holds during immediately after the time of existence of Y (9) pH measure V and T (10) pH measure U and S, then S is greater than T